STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDH1_1Malate dehydrogenase. (338 aa)    
Predicted Functional Partners:
mcsA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.991
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.991
cit-1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.991
got2
Aspartate aminotransferase.
   
 0.983
ACLY
ATP-citrate synthase.
  
 0.970
AAT2
Aspartate aminotransferase.
   
 0.970
pyc_0
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.968
acuE
Malate synthase; Belongs to the malate synthase family.
   
 0.955
malA_0
Malic enzyme.
  
 0.950
icdA
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.938
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.