STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (565 aa)    
Predicted Functional Partners:
DED81
Asparagine--tRNA ligase, cytoplasmic.
   
 0.982
Hypma_000185
WAPL domain-containing protein.
    
 
 0.889
Arpc4_2
Actin-related protein 2/3 complex subunit 4.
    
 
 0.889
Arpc4_1
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
    
 
 0.889
rad16
DNA repair protein rad16.
   
 0.887
Hypma_001660
DUF2156 domain-containing protein.
   
 0.880
DARS
Aspartate--tRNA ligase, cytoplasmic.
   
 0.880
asnS
Asparagine--tRNA ligase.
   
 0.880
DPS1
Aspartate--tRNA ligase, cytoplasmic.
   
 0.880
WRN_0
Werner syndrome ATP-dependent helicase.
    
 0.875
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.