node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADE1_1 | Hypma_008982 | A0A369K4S9 | A0A369JVH5 | Bifunctional purine biosynthetic protein ADE1. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.486 |
ADE1_1 | Hypma_009264 | A0A369K4S9 | A0A369JQP2 | Bifunctional purine biosynthetic protein ADE1. | Uncharacterized protein. | 0.405 |
ADE1_1 | Hypma_016377 | A0A369K4S9 | A0A369J0B7 | Bifunctional purine biosynthetic protein ADE1. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.405 |
ADE1_1 | Hypma_016378 | A0A369K4S9 | A0A369J5R1 | Bifunctional purine biosynthetic protein ADE1. | MYND-type domain-containing protein. | 0.405 |
ADE1_1 | pdxH | A0A369K4S9 | A0A369J9C6 | Bifunctional purine biosynthetic protein ADE1. | Pyridoxine/pyridoxamine 5'-phosphate oxidase. | 0.419 |
ADE1_1 | rnr-1 | A0A369K4S9 | A0A369J1Z2 | Bifunctional purine biosynthetic protein ADE1. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.406 |
GAD2 | Hypma_008982 | A0A369JWJ9 | A0A369JVH5 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.461 |
GAD2 | Hypma_016377 | A0A369JWJ9 | A0A369J0B7 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.405 |
GAD2 | SDH2 | A0A369JWJ9 | A0A369J9Q8 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.608 |
GAD2 | pgmA | A0A369JWJ9 | A0A369JTH4 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | Phosphoglucomutase; Belongs to the phosphohexose mutase family. | 0.760 |
GAD2 | sdh1 | A0A369JWJ9 | A0A369JGL2 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.591 |
Hypma_008982 | ADE1_1 | A0A369JVH5 | A0A369K4S9 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Bifunctional purine biosynthetic protein ADE1. | 0.486 |
Hypma_008982 | GAD2 | A0A369JVH5 | A0A369JWJ9 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | 0.461 |
Hypma_008982 | Hypma_009264 | A0A369JVH5 | A0A369JQP2 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Uncharacterized protein. | 0.786 |
Hypma_008982 | Hypma_016377 | A0A369JVH5 | A0A369J0B7 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.883 |
Hypma_008982 | Hypma_016378 | A0A369JVH5 | A0A369J5R1 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | MYND-type domain-containing protein. | 0.786 |
Hypma_008982 | SDH2 | A0A369JVH5 | A0A369J9Q8 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.486 |
Hypma_008982 | pdxH | A0A369JVH5 | A0A369J9C6 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Pyridoxine/pyridoxamine 5'-phosphate oxidase. | 0.906 |
Hypma_008982 | pgmA | A0A369JVH5 | A0A369JTH4 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Phosphoglucomutase; Belongs to the phosphohexose mutase family. | 0.622 |
Hypma_008982 | rnr-1 | A0A369JVH5 | A0A369J1Z2 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.461 |