STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ash2Set1 complex component ash2. (634 aa)    
Predicted Functional Partners:
Rbbp5
Retinoblastoma-binding protein 5.
    
 0.997
SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific.
    
 0.994
Wdr82
WD repeat-containing protein 82.
   
 0.967
Hypma_007364
Uncharacterized protein.
    
 0.955
H4.1_3
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.945
Hypma_003666
F-box domain-containing protein.
    
 0.945
H4.1_0
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.945
Hypma_002851
Uncharacterized protein.
   
 
 0.940
umv1
Spore development regulator umv1.
   
 
 0.940
ADO2
Adagio protein 2.
    
 
 0.933
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.