Hypma_003231 protein (Hypsizygus marmoreus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

Hypma_003231

Uncharacterized protein. (323 aa)

Predicted Functional Partners:

nuc-2

0.685

ppe1

0.584

ned-8

0.550

UBIQ

0.550

rga3

0.537

Hypma_007549

0.537

MYO2

0.533

Hypma_007418

0.533

Hypma_008008

0.527

ypt-1

0.524

Your Current Organism:

Hypsizygus marmoreus

NCBI taxonomy Id: 39966
Other names: H. marmoreus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hypma_003231	Hypma_007418	A0A369K4I4	A0A369JXH5	Uncharacterized protein.	Uncharacterized protein.	0.533
Hypma_003231	Hypma_007549	A0A369K4I4	A0A369K308	Uncharacterized protein.	BRCT domain-containing protein.	0.537
Hypma_003231	Hypma_008008	A0A369K4I4	A0A369JTX0	Uncharacterized protein.	Putative CDP-alcohol phosphatidyltransferase class-I family protein C22A12.08c.	0.527
Hypma_003231	MYO2	A0A369K4I4	A0A369JPN0	Uncharacterized protein.	Myosin-2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.533
Hypma_003231	UBIQ	A0A369K4I4	A0A369JZX3	Uncharacterized protein.	Ubiquitin.	0.550
Hypma_003231	ned-8	A0A369K4I4	A0A369JL99	Uncharacterized protein.	NEDD8.	0.550
Hypma_003231	nuc-2	A0A369K4I4	A0A369JM82	Uncharacterized protein.	Ankyrin repeat protein nuc-2.	0.685
Hypma_003231	ppe1	A0A369K4I4	A0A369JH15	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.584
Hypma_003231	rga3	A0A369K4I4	A0A369J6M0	Uncharacterized protein.	Putative Rho-type GTPase-activating protein 3.	0.537
Hypma_003231	ypt-1	A0A369K4I4	A0A369JPK0	Uncharacterized protein.	GTP-binding protein ypt1.	0.524
Hypma_007418	Hypma_003231	A0A369JXH5	A0A369K4I4	Uncharacterized protein.	Uncharacterized protein.	0.533
Hypma_007418	nuc-2	A0A369JXH5	A0A369JM82	Uncharacterized protein.	Ankyrin repeat protein nuc-2.	0.537
Hypma_007418	ppe1	A0A369JXH5	A0A369JH15	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.424
Hypma_007418	rga3	A0A369JXH5	A0A369J6M0	Uncharacterized protein.	Putative Rho-type GTPase-activating protein 3.	0.637
Hypma_007549	Hypma_003231	A0A369K308	A0A369K4I4	BRCT domain-containing protein.	Uncharacterized protein.	0.537
Hypma_007549	UBIQ	A0A369K308	A0A369JZX3	BRCT domain-containing protein.	Ubiquitin.	0.849
Hypma_007549	ned-8	A0A369K308	A0A369JL99	BRCT domain-containing protein.	NEDD8.	0.607
Hypma_007549	nuc-2	A0A369K308	A0A369JM82	BRCT domain-containing protein.	Ankyrin repeat protein nuc-2.	0.537
Hypma_008008	Hypma_003231	A0A369JTX0	A0A369K4I4	Putative CDP-alcohol phosphatidyltransferase class-I family protein C22A12.08c.	Uncharacterized protein.	0.527
Hypma_008008	nuc-2	A0A369JTX0	A0A369JM82	Putative CDP-alcohol phosphatidyltransferase class-I family protein C22A12.08c.	Ankyrin repeat protein nuc-2.	0.946

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Network Stats

number of nodes:

4

number of edges:

5

average node degree:

2.5

avg. local clustering coefficient:

0.833

expected number of edges:

3

PPI enrichment p-value:

0.157

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045226

Extracellular polysaccharide biosynthetic process

3 of 8

1.95

1.04

0.0099

GO:0009225

Nucleotide-sugar metabolic process

3 of 13

1.74

0.98

0.0110

GO:0019305

dTDP-rhamnose biosynthetic process

2 of 2

2.37

0.97

0.0167

GO:1901137

Carbohydrate derivative biosynthetic process

5 of 133

0.95

0.6

0.0167

GO:1901135

Carbohydrate derivative metabolic process

6 of 196

0.86

0.55

0.0167

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2951

Mixed, incl. Extracellular polysaccharide metabolic process, and Glycosyltransferase subfamily 4-like, N-terminal domain

10 of 16

2.17

6.92

8.23e-18

CL:2970

Mixed, incl. Glycosyl transferase, family 1, and Glycosyl transferase family group 2

6 of 6

2.37

5.01

5.49e-11

CL:2947

Mixed, incl. Polysaccharide biosynthetic process, and Glycosyl transferases group 1

11 of 62

1.62

3.85

1.06e-15

CL:2954

dTDP-rhamnose metabolic process, and Polyketide sugar unit biosynthesis

4 of 5

2.28

3.01

1.10e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ane00525

Acarbose and validamycin biosynthesis

2 of 2

2.37

1.18

0.0065

ane00523

Polyketide sugar unit biosynthesis

2 of 2

2.37

1.18

0.0065

ane00521

Streptomycin biosynthesis

2 of 3

2.2

1.17

0.0065

ane00541

O-Antigen nucleotide sugar biosynthesis

2 of 7

1.83

1.02

0.0097

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13692

Glycosyl transferases group 1

3 of 20

1.55

0.71

0.0362

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001296

Glycosyl transferase, family 1

3 of 10

1.85

0.99

0.0119

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