STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISA1Iron-sulfur assembly protein 1. (206 aa)    
Predicted Functional Partners:
ISU1
Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
  
 0.939
Hypma_011783
Cysteine desulfurase, mitochondrial.
  
 
 0.888
NIFU4
NifU-like protein 4, mitochondrial.
  
 
 0.883
grx4
Monothiol glutaredoxin-4.
  
 0.863
GRX5
Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 0.859
ustD
Cysteine desulfurase-like protein ustD.
  
 
 0.851
egt-2
Hercynylcysteine sulfoxide lyase.
  
 
 0.851
LIA1
Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
    
 
 0.849
CAF17
Putative transferase CAF17, mitochondrial.
  
 
 0.762
YAH1
Adrenodoxin, mitochondrial.
  
 
 0.757
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.