STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hypma_014011Uncharacterized protein. (834 aa)    
Predicted Functional Partners:
Hypma_007510
Protein kinase domain-containing protein.
    
 0.935
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
    
 0.660
ITSN2
Intersectin-2.
     
 0.641
PTPRG
Receptor-type tyrosine-protein phosphatase gamma.
    
  0.638
rad50
DNA repair protein rad50.
    
  0.591
Hypma_013440
Uncharacterized protein.
    
 0.581
Hypma_006573
Uncharacterized protein.
    
 0.581
apm2
AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.
    
  0.557
H4.1_3
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.554
Hypma_003666
F-box domain-containing protein.
    
  0.554
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.