node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDH30615.1 | SDH30620.1 | SAMN04489720_0866 | SAMN04489720_0867 | Predicted arabinose efflux permease, MFS family. | DivIVA domain-containing protein. | 0.561 |
SDH30615.1 | SDH30627.1 | SAMN04489720_0866 | SAMN04489720_0868 | Predicted arabinose efflux permease, MFS family. | DivIVA domain-containing protein. | 0.461 |
SDH30615.1 | folD | SAMN04489720_0866 | SAMN04489720_0863 | Predicted arabinose efflux permease, MFS family. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.436 |
SDH30615.1 | glyA | SAMN04489720_0866 | SAMN04489720_0864 | Predicted arabinose efflux permease, MFS family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.483 |
SDH30620.1 | SDH30615.1 | SAMN04489720_0867 | SAMN04489720_0866 | DivIVA domain-containing protein. | Predicted arabinose efflux permease, MFS family. | 0.561 |
SDH30620.1 | SDH30627.1 | SAMN04489720_0867 | SAMN04489720_0868 | DivIVA domain-containing protein. | DivIVA domain-containing protein. | 0.623 |
SDH30627.1 | SDH30615.1 | SAMN04489720_0868 | SAMN04489720_0866 | DivIVA domain-containing protein. | Predicted arabinose efflux permease, MFS family. | 0.461 |
SDH30627.1 | SDH30620.1 | SAMN04489720_0868 | SAMN04489720_0867 | DivIVA domain-containing protein. | DivIVA domain-containing protein. | 0.623 |
folD | SDH30615.1 | SAMN04489720_0863 | SAMN04489720_0866 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Predicted arabinose efflux permease, MFS family. | 0.436 |
folD | glyA | SAMN04489720_0863 | SAMN04489720_0864 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.991 |
glyA | SDH30615.1 | SAMN04489720_0864 | SAMN04489720_0866 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Predicted arabinose efflux permease, MFS family. | 0.483 |
glyA | folD | SAMN04489720_0864 | SAMN04489720_0863 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.991 |