STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDH66211.1DNA-directed RNA polymerase specialized sigma subunit, sigma24 family. (571 aa)    
Predicted Functional Partners:
SDH79769.1
2-oxoisovalerate dehydrogenase E1 component.
  
 0.993
SDH92941.1
2-oxoglutarate dehydrogenase E1 component.
  
 0.948
SDH10259.1
Glutamate synthase (NADH) large subunit.
     
 0.898
SDH13804.1
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.867
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.826
SDH30209.1
Pyruvate dehydrogenase E1 component beta subunit.
   
  0.824
SDH52700.1
Pyruvate dehydrogenase E1 component beta subunit.
   
  0.824
SDH99168.1
Pyruvate dehydrogenase E1 component beta subunit.
   
  0.824
SDH77176.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.814
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.782
Your Current Organism:
Agrococcus jejuensis
NCBI taxonomy Id: 399736
Other names: A. jejuensis, Agrococcus jejuensis Lee 2008, DSM 22002, JCM 14256, KCTC 19198, strain SSW1-48
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.