STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDH92185.1hydroxymethylglutaryl-CoA synthase. (378 aa)    
Predicted Functional Partners:
SDH92206.1
3-hydroxy-3-methylglutaryl-coenzyme A reductase.
 
 0.993
SDH92272.1
Diphosphomevalonate decarboxylase.
 
 
 0.989
SDH92246.1
Phosphomevalonate kinase.
 
     0.955
SDH92296.1
Mevalonate kinase.
 
     0.955
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.953
SDH12153.1
3-hydroxyacyl-CoA dehydrogenase.
   
 
  0.840
SDH12938.1
2-oxoglutarate dehydrogenase E2 component.
   
 
  0.837
SDH67743.1
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 0.668
SDH92160.1
Hypothetical protein.
       0.509
SDH30199.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
   
 
  0.491
Your Current Organism:
Agrococcus jejuensis
NCBI taxonomy Id: 399736
Other names: A. jejuensis, Agrococcus jejuensis Lee 2008, DSM 22002, JCM 14256, KCTC 19198, strain SSW1-48
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