STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI01309.1Dihydrofolate reductase. (185 aa)    
Predicted Functional Partners:
SDI01390.1
Dihydrofolate reductase.
 
     0.798
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.740
SDI01337.1
Hypothetical protein.
       0.610
SDI01361.1
Hypothetical protein.
       0.610
SDH39300.1
Dihydroneopterin aldolase/dihydropteroate synthase,TIGR01496; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
 0.584
SDH85870.1
RibD C-terminal domain-containing protein.
  
     0.565
SDI01276.1
Acetyltransferase (GNAT) domain-containing protein.
  
    0.521
SDH43913.1
Dihydrofolate reductase.
  
     0.494
SDH49342.1
Uncharacterized conserved protein YndB, AHSA1/START domain.
  
     0.422
Your Current Organism:
Agrococcus jejuensis
NCBI taxonomy Id: 399736
Other names: A. jejuensis, Agrococcus jejuensis Lee 2008, DSM 22002, JCM 14256, KCTC 19198, strain SSW1-48
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