Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Spro_1237Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (179 aa)    
Predicted Functional Partners:
Spro_2604
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: yen:YE2102 putative pyruvate-flavodoxin oxidoreductase.
 
   
 0.754
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: sgl:SG0861 ferric uptake regulation protein; Belongs to the Fur family.
  
  
 0.728
Spro_1238
PFAM: CopG domain protein DNA-binding domain protein; KEGG: ypi:YpsIP31758_2899 transcriptional regulator, CopG family.
 
  
 0.691
Spro_3419
PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase.
   
    0.607
seqA
SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
  
 0.506
Spro_1241
TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: yen:YE2967 phosphoglucomutase.
 
   
 0.503
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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