STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spro_1237Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (179 aa)    
Predicted Functional Partners:
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: sgl:SG0861 ferric uptake regulation protein; Belongs to the Fur family.
  
  
 0.658
Spro_1238
PFAM: CopG domain protein DNA-binding domain protein; KEGG: ypi:YpsIP31758_2899 transcriptional regulator, CopG family.
 
  
 0.625
Spro_3419
PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase.
   
    0.615
Spro_2604
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: yen:YE2102 putative pyruvate-flavodoxin oxidoreductase.
 
   
 0.606
seqA
SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
  
 0.487
Spro_3272
PFAM: ribonucleotide reductase; KEGG: yen:YE1392 ribonucleoside-diphosphate reductase 1 beta chain.
 
    0.449
Spro_3271
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.431
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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