STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spro_1378PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: yen:YE2881 hypothetical protein. (113 aa)    
Predicted Functional Partners:
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
  
 0.675
Spro_0326
KEGG: eca:ECA0560 putative plasmid transfer protein.
   
 
 0.666
Spro_4096
KEGG: eca:ECA0560 putative plasmid transfer protein.
   
 
 0.666
Spro_4179
KEGG: eca:ECA0560 putative plasmid transfer protein.
   
 
 0.666
Spro_1379
PFAM: GCN5-related N-acetyltransferase; KEGG: ngo:NGO1928 putative acetyltransferase.
       0.598
Spro_3393
KEGG: kpn:KPN_02277 putative nucleoprotein/polynucleotide-associated enzyme.
  
     0.557
Spro_1380
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfo:Pfl_2438 transcriptional regulator, LysR family.
       0.482
Spro_3510
PFAM: amino acid-binding ACT domain protein; KEGG: ypm:YP_2685 glycine cleavage system regulatory protein.
  
     0.444
Spro_2803
PFAM: YebG family protein; KEGG: yen:YE1786 hypothetical protein.
  
     0.431
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
   
 0.420
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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