Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Spro_1925PFAM: protein of unknown function UPF0227; KEGG: ypi:YpsIP31758_1593 hypothetical protein; Belongs to the UPF0227 family. (180 aa)    
Predicted Functional Partners:
Spro_2658
KEGG: yps:YPTB2139 hypothetical protein.
  
     0.770
Spro_1250
KEGG: eca:ECA1344 hypothetical protein.
  
     0.753
crl
Transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.
  
     0.727
Spro_0456
PFAM: protein of unknown function DUF1107; KEGG: ent:Ent638_0395 protein of unknown function DUF1107.
  
     0.723
zapC
Protein of unknown function DUF1379; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.716
viaA
SMART: von Willebrand factor type A; KEGG: ypi:YpsIP31758_0004 protein ViaA.
  
     0.715
Spro_3603
PFAM: protein of unknown function DUF1407; KEGG: yen:YE1079 hypothetical protein.
  
     0.707
Spro_1921
PFAM: protein of unknown function DUF1425; KEGG: ypi:YpsIP31758_1589 putative lipoprotein.
 
   
 0.700
Spro_0965
PFAM: protein of unknown function DUF1100 hydrolase family protein; KEGG: yen:YE3204 hypothetical protein; Belongs to the UPF0255 family.
  
   
 0.691
nagZ
Glycoside hydrolase family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
  
  
 0.666
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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