STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spro_1972Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ecj:JW3046 DNA-binding transcriptional repressor. (326 aa)    
Predicted Functional Partners:
Spro_0120
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: pol:Bpro_4573 transcriptional regulator, LacI family.
  
     0.773
Spro_0750
Transcriptional regulator, LacI family; TIGRFAM: D-fructose-responsive transcription factor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE0661 putative fructose repressor.
  
     0.718
Spro_4344
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor.
    
 
 0.661
Spro_1973
PFAM: glycoside hydrolase family 42 domain 5 loop region; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: aha:AHA_0205 evolved beta-galactosidase alpha-subunit.
 
   
 0.560
Spro_4270
Dihydroxyacetone kinase, phosphotransfer subunit; KEGG: yen:YE0542 multifunctional PTS-system sugar transferase; TIGRFAM: phosphocarrier, HPr family; dihydroxyacetone kinase, phosphotransfer subunit; PFAM: phosphocarrier HPr protein; PTS system fructose subfamily IIA component; PEP-utilising protein mobile region; PEP-utilising protein domain protein; Belongs to the PEP-utilizing enzyme family.
   
 
 0.551
Spro_1970
KEGG: vvy:VV2646 putative isomerase.
 
     0.543
Spro_1975
PFAM: amino acid permease-associated region; KEGG: ecp:ECP_3169 hypothetical transporter YgjI.
 
     0.506
Spro_1974
PFAM: conserved hypothetical protein; KEGG: vvy:VV2643 evolved beta-D-galactosidase, beta subunit; cryptic gene.
       0.449
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
Server load: medium (44%) [HD]