Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Spro_1997TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: yen:YE2425 putative inner membrane protein. (366 aa)    
Predicted Functional Partners:
Spro_2811
PFAM: EAL domain protein; KEGG: ent:Ent638_2384 diguanylate phosphodiesterase.
 
  
 0.830
Spro_3245
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: ypi:YpsIP31758_2710 protein rtn.
 
  
 0.812
Spro_4748
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: ypi:YpsIP31758_4059 cyclic diguanylate phosphodiesterase (EAL) domain protein.
 
  
 0.795
Spro_3543
Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: GGDEF domain containing protein; KEGG: kpn:KPN_02828 putative cytochrome c-type biogenesis protein.
 
  
 0.785
Spro_0152
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; KEGG: ypp:YPDSF_3363 membrane protein.
  
  
 0.777
Spro_4412
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: ypi:YpsIP31758_0397 putative diguanylate cyclase/cyclic diguanylate phosphodiesterase protein.
 
  
 0.743
Spro_1518
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: kpn:KPN_03274 hypothetical protein.
 
  
 0.732
Spro_4342
Multi-sensor hybrid histidine kinase; KEGG: ypi:YpsIP31758_0469 putative aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.677
Spro_2163
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: eca:ECA1841 hypothetical protein.
 
  
 0.676
Spro_0790
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: ypm:YP_0304 two-component regulatory protein.
 
  
 0.660
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.