Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nagKROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (306 aa)    
Predicted Functional Partners:
Spro_1228
TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: stm:STM0685 Sugar Specific PTS family, n-acetylglucosamine-specific enzyme IIABC.
  
 0.975
Spro_1226
KEGG: yen:YE2980 putative N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase.
 
 
 0.928
Spro_2576
PFAM: ROK family protein; KEGG: pin:Ping_1332 ROK family protein.
  
  
 
0.911
Spro_3450
TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: yen:YE1205 PTS system, glucose-specific IIA component.
  
 
 0.905
murQ
Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
    
 0.905
Spro_2003
TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; lipoprotein releasing system, transmembrane protein LolE; PFAM: protein of unknown function DUF214; KEGG: ent:Ent638_1633 lipoprotein releasing system, transmembrane protein LolE.
      0.812
Spro_2283
PFAM: ROK family protein; KEGG: yen:YE2023 putative ROK family transcriptional regulatory protein.
 
     0.775
cobB
PFAM: Silent information regulator protein Sir2; KEGG: yen:YE1714 putative Sir2 family protein; Belongs to the sirtuin family. Class III subfamily.
  
    0.768
Spro_2323
TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: eca:ECA0860 PTS system, IIabc component.
  
 
 0.767
Spro_1225
PFAM: ROK family protein; KEGG: yen:YE2981 putative N-acetylglucosamine regulatory protein.
  
     0.766
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
Server load: low (16%) [HD]