STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spro_2012Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: yen:YE1717 sensor protein kinase. (485 aa)    
Predicted Functional Partners:
Spro_2013
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_1608 transcriptional regulatory protein PhoP.
 0.999
Spro_4342
Multi-sensor hybrid histidine kinase; KEGG: ypi:YpsIP31758_0469 putative aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.873
rcsD
Multi-sensor signal transduction histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
 
 0.765
Spro_4874
PFAM: AsmA family protein; KEGG: yen:YE0040 possible exported protein.
  
     0.759
Spro_0478
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_3607 transcriptional regulatory protein BasR/PmrA.
 
 0.751
Spro_2590
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE2083 two-component regulatory system, response regulator protein.
 
 
 0.730
Spro_1285
Hpt sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: extracellular solute-binding protein family 3; KEGG: pfo:Pfl_1864 Hpt sensor hybrid histidine kinase.
 
 
 
 0.714
Spro_0790
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: ypm:YP_0304 two-component regulatory protein.
  
 
0.708
Spro_4810
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ecp:ECP_4122 transcriptional regulatory protein CpxR.
 
 
 0.701
Spro_1759
PFAM: UvrD/REP helicase; KEGG: yen:YE1586 putative helicase IV.
  
    0.699
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.