Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Spro_2139KEGG: asa:ASA_3891 serine transporter. (427 aa)    
Predicted Functional Partners:
dps
Ferritin Dps family protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
    
   0.714
Spro_4786
O-succinylhomoserine (thiol)-lyase; KEGG: ypi:YpsIP31758_0121 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
      
 0.669
Spro_1629
KEGG: yen:YE1472 L-serine dehydratase 2; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
  
 0.659
Spro_2140
PFAM: periplasmic binding protein; KEGG: eca:ECA3241 ABC transporter, substrate binding protein.
 
     0.590
Spro_2688
PFAM: Ferritin Dps family protein; KEGG: vco:VC0395_A2381 DPS family protein; Belongs to the Dps family.
    
   0.524
Spro_1669
PFAM: protein of unknown function DUF535; KEGG: yen:YE1513 putative virulence factor.
  
     0.496
Spro_2810
KEGG: ypi:YpsIP31758_2355 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
  
 0.441
Spro_2138
Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: kpn:KPN_02082 gluconate dehydrogenase cytochrome c subunit, putative.
       0.418
Spro_2136
Gluconate 2-dehydrogenase (acceptor); KEGG: kpn:KPN_02084 hypothetical protein.
       0.406
Spro_2137
Gluconate 2-dehydrogenase (acceptor); PFAM: glucose-methanol-choline oxidoreductase; KEGG: kpn:KPN_02083 monooxygenase, FAD-binding; glucose-methanol-choline oxidoreductase.
       0.406
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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