Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdtJSmall multidrug resistance protein; Catalyzes the excretion of spermidine. (122 aa)    
Predicted Functional Partners:
mdtI
Small multidrug resistance protein; Catalyzes the excretion of spermidine.
 
  
 0.997
Spro_0415
PFAM: small multidrug resistance protein; KEGG: stm:STM4338 putative DMT superfamily transport protein.
 
   
 0.844
Spro_2603
PFAM: small multidrug resistance protein; KEGG: yen:YE2101 quaternary ammonium compound-resistance protein.
 
   
 0.785
mdtG
PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1610 putative MFS-family transport protein.
      
 0.561
mdtD
PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1106 hypothetical protein.
      
 0.534
srkA
Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
      
 0.510
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
      
 0.461
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
      
 0.404
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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