STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (396 aa)    
Predicted Functional Partners:
Spro_3239
PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: yen:YE1438 putative D-mannonate oxidoreductase.
 
 
 0.983
Spro_4320
PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: ypi:YpsIP31758_0493 altronate dehydratase.
 
 
 0.982
Spro_3566
PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0920 probable carbohydrate oxidoreductase.
 
 
 0.975
uxaC
PFAM: Glucuronate isomerase; KEGG: yen:YE3708 uronate isomerase.
 
  
 0.965
Spro_2462
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ecs:ECs3630 putative oxidoreductase.
 
 
 0.929
Spro_4707
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ent:Ent638_3295 2-deoxy-D-gluconate 3-dehydrogenase.
  
 
 0.913
Spro_3563
PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0917 putative starvation sensing mandelate racemase / muconate lactonizing enzyme.
    
 0.911
Spro_4750
PFAM: PfkB domain protein; KEGG: ypi:YpsIP31758_4062 2-dehydro-3-deoxygluconokinase.
 
  
 0.910
Spro_0059
PFAM: PfkB domain protein; KEGG: kpn:KPN_03913 putative kinase.
 
  
 0.854
Spro_1608
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.800
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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