STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spro_3350PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: yen:YE1300 putative metal resistance protein. (678 aa)    
Predicted Functional Partners:
Spro_3348
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: yen:YE1302 putative metal resistance protein.
 
 
 0.971
Spro_3349
PFAM: DSBA oxidoreductase; KEGG: yen:YE1301 putative metal resistance protein.
 
 
 0.958
Spro_3385
TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: yen:YE1269 thiol:disulfide interchange protein DsbE.
 
 
 0.847
Spro_3351
KEGG: yen:YE1299 putative metal resistance protein.
     
 0.797
msrB
TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; KEGG: ypi:YpsIP31758_1986 methionine-R-sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
   
 
 0.733
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.710
Spro_0983
PFAM: DSBA oxidoreductase; KEGG: sgl:SG2236 thiol:disulfide interchange protein.
  
 
 0.621
Spro_3891
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.621
Spro_4889
PFAM: DSBA oxidoreductase; KEGG: yen:YE0020 secreted thiol:disulfide interchange protein DsbA.
  
 
 0.621
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.584
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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