STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spro_3489Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA1900 nitrate/nitrite sensor protein. (560 aa)    
Predicted Functional Partners:
Spro_3490
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; KEGG: yen:YE1153 nitrate/nitrite response regulator protein NarP.
 
 0.991
Spro_2900
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: eca:ECA2028 nitrate/nitrite response regulator.
 
 0.983
Spro_0132
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: ypi:YpsIP31758_4080 transcriptional regulatory protein UhpA.
 
 
 0.752
Spro_3589
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; Sigma-70 region 4 type 2; KEGG: reh:H16_B0523 response regulator, NarL-family.
 
 
 0.701
napD
NapD family protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
 
    0.676
Spro_1848
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: yen:YE1831 response regulator protein.
 
 
 0.667
Spro_0790
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: ypm:YP_0304 two-component regulatory protein.
 
  
 0.584
Spro_2443
KEGG: pfl:PFL_2568 sensory box transcriptional regulator, LuxR family; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.568
Spro_1286
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: pfl:PFL_2955 DNA-binding response regulator, LuxR family.
 
 
 0.519
Spro_0505
PFAM: Sterol-binding domain protein; KEGG: yen:YE0451 putative lipid carrier protein.
 
     0.499
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.