STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spro_4207Transcriptional regulator, LacI family; KEGG: yen:YE0550A sucrose operon repressor; TIGRFAM: D-fructose-responsive transcription factor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator. (347 aa)    
Predicted Functional Partners:
Spro_2081
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: kpn:KPN_03263 putative bacterial regulatory protein, LacI.
  
     0.772
Spro_3600
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_0927 sugar-binding transcriptional regulator, LacI family.
  
     0.770
Spro_4205
TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE0552 PTS system, sucrose-specific IIBC component.
 
   
 0.765
Spro_3114
PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb20366 putative transcriptional regulator protein.
  
     0.764
Spro_4206
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
  
 0.758
Spro_4344
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor.
    
 
 0.661
Spro_4203
PFAM: PfkB domain protein; KEGG: yen:YE0554 fructokinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.629
Spro_4204
KEGG: plu:plu1882 hypothetical protein.
 
     0.603
Spro_4270
Dihydroxyacetone kinase, phosphotransfer subunit; KEGG: yen:YE0542 multifunctional PTS-system sugar transferase; TIGRFAM: phosphocarrier, HPr family; dihydroxyacetone kinase, phosphotransfer subunit; PFAM: phosphocarrier HPr protein; PTS system fructose subfamily IIA component; PEP-utilising protein mobile region; PEP-utilising protein domain protein; Belongs to the PEP-utilizing enzyme family.
   
 
 0.551
sufS
Cysteine desulfurase, SufS subfamily; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
    
  0.527
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.