node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_3575 | Spro_4363 | Spro_3575 | Spro_4363 | KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.882 |
Spro_3575 | Spro_4366 | Spro_3575 | Spro_4366 | KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3758 probable ABC transporter ATP-binding protein. | 0.610 |
Spro_3575 | kdsA | Spro_3575 | Spro_1994 | KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: ypi:YpsIP31758_2062 3-deoxy-8-phosphooctulonate synthase. | 0.892 |
Spro_3575 | kdsB | Spro_3575 | Spro_1719 | KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.879 |
Spro_3575 | lpxC | Spro_3575 | Spro_0767 | KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.849 |
Spro_4361 | Spro_4362 | Spro_4361 | Spro_4362 | TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein. | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | 0.825 |
Spro_4361 | Spro_4363 | Spro_4361 | Spro_4363 | TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.764 |
Spro_4361 | Spro_4366 | Spro_4361 | Spro_4366 | TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein. | ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3758 probable ABC transporter ATP-binding protein. | 0.764 |
Spro_4361 | lptA | Spro_4361 | Spro_4365 | TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein. | Cell envelope biogenesis YhbN; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.749 |
Spro_4361 | lptC | Spro_4361 | Spro_4364 | TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein. | Protein of unknown function DUF1239; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.764 |
Spro_4362 | Spro_4361 | Spro_4362 | Spro_4361 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein. | 0.825 |
Spro_4362 | Spro_4363 | Spro_4362 | Spro_4363 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.987 |
Spro_4362 | Spro_4366 | Spro_4362 | Spro_4366 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3758 probable ABC transporter ATP-binding protein. | 0.931 |
Spro_4362 | kdsA | Spro_4362 | Spro_1994 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: ypi:YpsIP31758_2062 3-deoxy-8-phosphooctulonate synthase. | 0.988 |
Spro_4362 | kdsB | Spro_4362 | Spro_1719 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.880 |
Spro_4362 | lptA | Spro_4362 | Spro_4365 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | Cell envelope biogenesis YhbN; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.824 |
Spro_4362 | lptC | Spro_4362 | Spro_4364 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | Protein of unknown function DUF1239; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.882 |
Spro_4362 | lpxC | Spro_4362 | Spro_0767 | KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.874 |
Spro_4363 | Spro_3575 | Spro_4363 | Spro_3575 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS). | 0.882 |
Spro_4363 | Spro_4361 | Spro_4363 | Spro_4361 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein. | 0.764 |