STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolEXylose isomerase domain protein TIM barrel; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family. (298 aa)    
Predicted Functional Partners:
Spro_4659
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yen:YE4027 putative thiamine pyrophosphate-dependent protein; Belongs to the TPP enzyme family.
 
 
 0.993
iolG
Inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
 
 
 0.992
Spro_4665
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: stm:STM4435 putative cytoplasmic protein.
 
 
  0.991
Spro_2393
Inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: pst:PSPTO_3047 myo-inositol 2-dehydrogenase, putative.
 
 
 0.982
Spro_4657
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_04676 putative epimerase/isomerase.
 
  
 0.947
Spro_2054
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_01796 putative epimerase/isomerase.
  
  
 
0.927
Spro_4660
PFAM: PfkB domain protein; KEGG: yen:YE4028 putative carbohydrate kinase.
  
 0.922
Spro_1442
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: yen:YE2867 hypothetical protein.
  
 0.919
Spro_4662
PFAM: Myo-inositol catabolism IolB domain protein; KEGG: yen:YE4030 hypothetical protein.
 
  
 0.910
Spro_3195
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: bsu:BG11855 unknown.
  
     0.702
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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