STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
Experiments
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[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (116 aa)    
Predicted Functional Partners:
ABP61864.1
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: sbo:SBO_2793 guanine-nucleotide binding protein.
 
 
 0.992
ABP61865.1
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: sfv:SFV_2775 HypC.
 
  
 0.978
ABP61866.1
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: ecv:APECO1_3796 protein required for maturation of hydrogenases; Belongs to the HypD family.
 
  
 0.973
ABP61867.1
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sec:SC2791 putative hydrogenase expression/formation protein.
 
  
 0.969
ABP61858.1
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; NADH dehydrogenase (ubiquinone), 30 kDa subunit; KEGG: stm:STM2849 hydrogenase 3 large subunit.
 
 
 0.880
ABP61849.1
(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.864
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 
 0.685
ABP61854.1
Hydrogenase 3 maturation peptidase Hycl, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; hydrogenase maturation protease HycI; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52, hydrogen uptake protein; KEGG: sec:SC2778 protease involved in processing C-terminal end of HycE.
 
  
 0.679
ABP61861.1
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sec:SC2785 hydrogenase-3, iron-sulfur subunit (part of FHL complex).
  
  
 0.669
ABP61855.1
PFAM: formate hydrogenlyase maturation HycH; KEGG: sec:SC2779 processing of HycE (part of the FHL complex).
 
  
 0.640
Your Current Organism:
Enterobacter sp. 638
NCBI taxonomy Id: 399742
Other names: E. sp. 638
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