node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFR31529.1 | SFR31767.1 | SAMN04490243_0264 | SAMN04490243_0353 | Nicotinamide-nucleotide amidase; Belongs to the CinA family. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.815 |
SFR31767.1 | SFR31529.1 | SAMN04490243_0353 | SAMN04490243_0264 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Nicotinamide-nucleotide amidase; Belongs to the CinA family. | 0.815 |
SFR31767.1 | SFR31773.1 | SAMN04490243_0353 | SAMN04490243_0355 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Hypothetical protein. | 0.709 |
SFR31767.1 | SFR32598.1 | SAMN04490243_0353 | SAMN04490243_0518 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.767 |
SFR31767.1 | SFR32869.1 | SAMN04490243_0353 | SAMN04490243_0567 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.642 |
SFR31767.1 | SFR47532.1 | SAMN04490243_0353 | SAMN04490243_1937 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | FAD/FMN-containing dehydrogenase. | 0.653 |
SFR31767.1 | SFR54628.1 | SAMN04490243_0353 | SAMN04490243_2821 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Signal transduction histidine kinase. | 0.648 |
SFR31767.1 | SFR54641.1 | SAMN04490243_0353 | SAMN04490243_2822 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.881 |
SFR31767.1 | adk | SAMN04490243_0353 | SAMN04490243_2789 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.678 |
SFR31767.1 | guaA | SAMN04490243_0353 | SAMN04490243_2271 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.630 |
SFR31767.1 | pyrE | SAMN04490243_0353 | SAMN04490243_0354 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.620 |
SFR31773.1 | SFR31767.1 | SAMN04490243_0355 | SAMN04490243_0353 | Hypothetical protein. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.709 |
SFR31773.1 | pyrE | SAMN04490243_0355 | SAMN04490243_0354 | Hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.824 |
SFR32598.1 | SFR31767.1 | SAMN04490243_0518 | SAMN04490243_0353 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.767 |
SFR32598.1 | SFR54628.1 | SAMN04490243_0518 | SAMN04490243_2821 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Signal transduction histidine kinase. | 0.410 |
SFR32598.1 | SFR54641.1 | SAMN04490243_0518 | SAMN04490243_2822 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.899 |
SFR32598.1 | adk | SAMN04490243_0518 | SAMN04490243_2789 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.499 |
SFR32598.1 | guaA | SAMN04490243_0518 | SAMN04490243_2271 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.531 |
SFR32869.1 | SFR31767.1 | SAMN04490243_0567 | SAMN04490243_0353 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.642 |
SFR32869.1 | adk | SAMN04490243_0567 | SAMN04490243_2789 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.835 |