A0A1X7SL51 protein (Amphimedon queenslandica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A1X7SL51

ANK_REP_REGION domain-containing protein. (343 aa)

Predicted Functional Partners:

A0A1X7SS43

0.475

A0A1X7TFZ2

0.471

A0A1X7UJ16

0.445

A0A1X7SEJ4

0.444

A0A1X7TFW2

0.430

A0A1X7U552

0.415

A0A1X7TH23

0.413

A0A1X7TX49

0.413

A0A1X7SLW7

0.408

A0A1X7TEX0

0.406

Your Current Organism:

Amphimedon queenslandica

NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.83

expected number of edges:

15

PPI enrichment p-value:

0.0417

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 114

1.55

3.35

2.24e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 55

1.78

4.0

1.47e-12

GO:0019843

rRNA binding

7 of 42

1.78

3.3

2.02e-09

GO:0003723

RNA binding

8 of 121

1.38

2.08

2.56e-08

GO:0000049

tRNA binding

4 of 28

1.72

1.74

0.00013

GO:0003676

Nucleic acid binding

9 of 504

0.81

0.76

5.43e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 63

1.72

3.82

8.73e-13

GO:0015935

Small ribosomal subunit

3 of 6

2.26

2.33

3.03e-05

GO:0005622

Intracellular anatomical structure

11 of 1355

0.47

0.41

0.00014

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:23342046

(2013) The genome sequences of Cellulomonas fimi and Cellvibrio gilvus reveal the cellulolytic strategies of two facultative anaerobes, transfer of Cellvibrio gilvus to the genus Cellulomonas, and proposal of Cellulomonas gilvus sp. nov.

3 of 32

1.53

0.95

0.0091

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:162

Ribosome

9 of 43

1.88

4.66

9.85e-14

CL:166

rRNA-binding

7 of 28

1.96

4.23

3.68e-11

CL:169

rRNA-binding

5 of 15

2.08

3.46

3.66e-08

CL:133

Translation, and Protein export

11 of 136

1.47

2.97

9.85e-14

CL:173

mRNA binding, and rRNA-binding

3 of 6

2.26

2.21

5.49e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sde03010

Ribosome

9 of 53

1.79

4.26

1.58e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 52

1.69

2.92

9.28e-09

GOCC:0022626

Cytosolic ribosome

5 of 29

1.8

2.55

1.03e-06

GOCC:0044391

Ribosomal subunit

5 of 33

1.74

2.44

1.23e-06

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 13

1.92

1.77

0.00024

GOCC:0043229

Intracellular organelle

9 of 280

1.07

1.29

3.19e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 55

1.78

4.11

4.44e-13

KW-0699

rRNA-binding

7 of 39

1.82

3.57

3.82e-10

KW-0820

tRNA-binding

3 of 19

1.76

1.43

0.0010

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (24%) [HD]

Permalink

Network

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About

node1	node2	node1 annotation	node2 annotation	score
A0A1X7SEJ4	A0A1X7SL51	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.444
A0A1X7SEJ4	A0A1X7SS43	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.490
A0A1X7SEJ4	A0A1X7TFW2	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.484
A0A1X7SEJ4	A0A1X7TFZ2	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.457
A0A1X7SEJ4	A0A1X7TX49	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.476
A0A1X7SEJ4	A0A1X7UJ16	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.430
A0A1X7SL51	A0A1X7SEJ4	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.444
A0A1X7SL51	A0A1X7SLW7	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.408
A0A1X7SL51	A0A1X7SS43	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.475
A0A1X7SL51	A0A1X7TEX0	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.406
A0A1X7SL51	A0A1X7TFW2	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.430
A0A1X7SL51	A0A1X7TFZ2	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.471
A0A1X7SL51	A0A1X7TH23	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.413
A0A1X7SL51	A0A1X7TX49	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.413
A0A1X7SL51	A0A1X7U552	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.415
A0A1X7SL51	A0A1X7UJ16	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.445
A0A1X7SLW7	A0A1X7SL51	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.408
A0A1X7SLW7	A0A1X7SS43	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.460
A0A1X7SLW7	A0A1X7TFZ2	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.429
A0A1X7SLW7	A0A1X7TX49	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.474