STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X7UC79Uncharacterized protein. (4110 aa)    
Predicted Functional Partners:
A0A1X7VQ10
RING-type domain-containing protein.
    
 0.472
A0A1X7VRY0
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.469
A0A1X7VBG1
Ubiquitin-like domain-containing protein.
    
  0.466
A0A1X7T1X8
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.453
A0A1X7VLR9
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.453
A0A1X7UP01
Uncharacterized protein.
    
 0.431
A0A1X7V1U2
VWFA domain-containing protein.
    
  0.422
A0A1X7VVB5
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.422
A0A1X7V2Y3
RING-type domain-containing protein.
    
  0.419
A0A1X7U0B6
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
 0.415
Your Current Organism:
Amphimedon queenslandica
NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.