STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X7UIB7Poly [ADP-ribose] polymerase. (685 aa)    
Predicted Functional Partners:
A0A1X7VWP7
zf-CCHH domain-containing protein.
    
 
 0.779
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.734
A0A1X7V3L2
Uncharacterized protein.
    
 0.723
A0A1X7U7R0
Uncharacterized protein.
    
 0.720
A0A1X7V563
Uncharacterized protein.
    
 0.720
A0A1X7U768
SAP domain-containing protein.
   
 
 0.704
A0A1X7V1U2
VWFA domain-containing protein.
   
 
 0.683
A0A1X7V925
XPA_C domain-containing protein.
     
 0.674
A0A1X7U124
CPSF_A domain-containing protein.
   
 
 0.642
A0A1X7VVB5
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.642
Your Current Organism:
Amphimedon queenslandica
NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.