STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X7UZG71-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1253 aa)    
Predicted Functional Partners:
A0A1X7V712
Phosphoinositide phospholipase C.
  
 
0.952
A0A1X7UY67
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.938
A0A1X7VF58
PIPK domain-containing protein.
     
 0.919
A0A1X7UMY5
Uncharacterized protein.
     
 0.917
A0A1X7V9D8
Diacylglycerol kinase.
     
 0.917
A0A1X7VLT1
PIPK domain-containing protein.
     
 0.917
A0A1X7VU47
Diacylglycerol kinase.
     
 0.917
A0A1X7VMI1
Uncharacterized protein.
   
 
 0.916
A0A1X7UK12
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.913
A0A1X7VND2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.913
Your Current Organism:
Amphimedon queenslandica
NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005
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