STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X7V053DNA_mis_repair domain-containing protein. (697 aa)    
Predicted Functional Partners:
A0A1X7UEV3
Uncharacterized protein.
    
0.999
A0A1X7TRE7
Uncharacterized protein.
  
 
0.996
A0A1X7V197
DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.994
A0A1X7UB38
Uncharacterized protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.991
A0A1X7V4T2
TPR_REGION domain-containing protein.
   
 0.985
A0A1X7U1M9
DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.984
A0A1X7VW78
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
    
 0.973
A0A1X7UE18
Helicase ATP-binding domain-containing protein.
   
 0.946
A0A1X7VKX8
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.931
A0A1X7VQ10
RING-type domain-containing protein.
    
 
 0.884
Your Current Organism:
Amphimedon queenslandica
NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.