STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X7V5F7E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (273 aa)    
Predicted Functional Partners:
A0A1X7VA85
Uncharacterized protein.
    
 0.992
A0A1X7V4L6
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
   0.863
A0A1X7VRY0
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.838
A0A1X7UQP4
Glyceraldehyde-3-phosphate dehydrogenase.
   
 
 0.727
A0A1X7VGB6
DIX domain-containing protein.
    
 
 0.693
A0A1X7VRK5
ANK_REP_REGION domain-containing protein.
    
 0.634
A0A1X7UR37
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.610
A0A1X7VUH5
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.573
A0A1X7SUX8
Uncharacterized protein.
    
  0.553
A0A1X7UQQ6
Ubiquitin carboxyl-terminal hydrolase.
    
  0.553
Your Current Organism:
Amphimedon queenslandica
NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005
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