STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X7VJ15Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. (767 aa)    
Predicted Functional Partners:
A0A1X7UYB2
Uncharacterized protein.
   
 0.986
A0A1X7UZY3
WD_REPEATS_REGION domain-containing protein.
   
 0.901
A0A1X7VQ18
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.847
A0A1X7VL95
Uncharacterized protein.
    
 0.820
A0A1X7T1W6
Histone H3; Belongs to the histone H3 family.
    
 0.813
A0A1X7UTZ4
Histone domain-containing protein.
    
 0.813
I1G9C5_AMPQE
Histone H3; Belongs to the histone H3 family.
    
 0.813
A0A1X7U6C2
Uncharacterized protein.
   
 0.804
A0A1X7VGZ6
PHD-type domain-containing protein.
   
 0.804
A0A1X7UWG6
HMG box domain-containing protein.
   
 0.799
Your Current Organism:
Amphimedon queenslandica
NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.