STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I1EJB6_AMPQECleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (195 aa)    
Predicted Functional Partners:
A0A1X7V5V1
RRM domain-containing protein.
   
 0.993
A0A1X7UKP2
Fip1 domain-containing protein.
   
 0.978
A0A1X7UKX9
Uncharacterized protein.
    
 0.962
A0A1X7V720
YTH domain-containing protein.
    
 
 0.959
A0A1X7VEH9
Uncharacterized protein.
    
 0.936
A0A1X7VH84
Uncharacterized protein.
    
 0.936
A0A1X7V4L5
RRM domain-containing protein.
   
 0.924
A0A1X7SH60
Cleavage and polyadenylation specificity factor subunit 2.
   
 
 0.879
A0A1X7VLD2
Cleavage and polyadenylation specificity factor subunit 2.
   
 
 0.879
A0A1X7V626
Uncharacterized protein.
     
 0.873
Your Current Organism:
Amphimedon queenslandica
NCBI taxonomy Id: 400682
Other names: A. queenslandica, Amphimedon queenslandica Hooper & Van Soest, 2006, Reniera sp. JGI-2005
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.