STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C0Q70_17070Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (475 aa)    
Predicted Functional Partners:
C0Q70_15207
Dihydrolipoyl dehydrogenase.
  
 0.992
C0Q70_10508
Transket_pyr domain-containing protein.
 
 0.986
C0Q70_13063
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.981
C0Q70_14902
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.930
C0Q70_01671
Transket_pyr domain-containing protein.
  
 0.916
C0Q70_13370
Transket_pyr domain-containing protein.
  
 0.908
C0Q70_08801
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.841
C0Q70_09751
Citrate synthase; Belongs to the citrate synthase family.
  
 0.813
C0Q70_07416
BPL/LPL catalytic domain-containing protein.
  
 0.809
C0Q70_00705
Uncharacterized protein.
  
 0.797
Your Current Organism:
Pomacea canaliculata
NCBI taxonomy Id: 400727
Other names: P. canaliculata
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.