C0Q70_02326 protein (Pomacea canaliculata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

C0Q70_02326

Uncharacterized protein. (386 aa)

Predicted Functional Partners:

C0Q70_00916

0.539

C0Q70_00915

0.539

C0Q70_10551

0.441

C0Q70_09048

0.441

C0Q70_09695

0.441

C0Q70_06204

0.441

C0Q70_00020

0.441

C0Q70_00197

0.441

Your Current Organism:

Pomacea canaliculata

NCBI taxonomy Id: 400727
Other names: P. canaliculata

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C0Q70_00020	C0Q70_00915	A0A2T7PVK9	A0A2T7PY06	Uncharacterized protein.	Protein kinase domain-containing protein.	0.993
C0Q70_00020	C0Q70_00916	A0A2T7PVK9	A0A2T7PY03	Uncharacterized protein.	Uncharacterized protein.	0.993
C0Q70_00020	C0Q70_02326	A0A2T7PVK9	A0A2T7PPL6	Uncharacterized protein.	Uncharacterized protein.	0.441
C0Q70_00197	C0Q70_00915	A0A2T7PW09	A0A2T7PY06	Uncharacterized protein.	Protein kinase domain-containing protein.	0.993
C0Q70_00197	C0Q70_00916	A0A2T7PW09	A0A2T7PY03	Uncharacterized protein.	Uncharacterized protein.	0.993
C0Q70_00197	C0Q70_02326	A0A2T7PW09	A0A2T7PPL6	Uncharacterized protein.	Uncharacterized protein.	0.441
C0Q70_00915	C0Q70_00020	A0A2T7PY06	A0A2T7PVK9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.993
C0Q70_00915	C0Q70_00197	A0A2T7PY06	A0A2T7PW09	Protein kinase domain-containing protein.	Uncharacterized protein.	0.993
C0Q70_00915	C0Q70_00916	A0A2T7PY06	A0A2T7PY03	Protein kinase domain-containing protein.	Uncharacterized protein.	0.999
C0Q70_00915	C0Q70_02326	A0A2T7PY06	A0A2T7PPL6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.539
C0Q70_00915	C0Q70_06204	A0A2T7PY06	A0A2T7PNC3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.993
C0Q70_00915	C0Q70_09048	A0A2T7PY06	A0A2T7P8Q8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.993
C0Q70_00915	C0Q70_09695	A0A2T7PY06	A0A2T7PAI9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.993
C0Q70_00915	C0Q70_10551	A0A2T7PY06	A0A2T7P3H0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.993
C0Q70_00916	C0Q70_00020	A0A2T7PY03	A0A2T7PVK9	Uncharacterized protein.	Uncharacterized protein.	0.993
C0Q70_00916	C0Q70_00197	A0A2T7PY03	A0A2T7PW09	Uncharacterized protein.	Uncharacterized protein.	0.993
C0Q70_00916	C0Q70_00915	A0A2T7PY03	A0A2T7PY06	Uncharacterized protein.	Protein kinase domain-containing protein.	0.999
C0Q70_00916	C0Q70_02326	A0A2T7PY03	A0A2T7PPL6	Uncharacterized protein.	Uncharacterized protein.	0.539
C0Q70_00916	C0Q70_06204	A0A2T7PY03	A0A2T7PNC3	Uncharacterized protein.	Uncharacterized protein.	0.993
C0Q70_00916	C0Q70_09048	A0A2T7PY03	A0A2T7P8Q8	Uncharacterized protein.	Uncharacterized protein.	0.993

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

22

PPI enrichment p-value:

9.53e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032543

Mitochondrial translation

5 of 45

2.0

2.94

4.08e-07

GO:0006412

Translation

10 of 291

1.49

2.78

2.17e-11

GO:0044238

Primary metabolic process

11 of 3249

0.48

0.4

0.00086

GO:0071704

Organic substance metabolic process

11 of 3666

0.43

0.35

0.0029

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 156

1.76

4.28

2.23e-14

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005762

Mitochondrial large ribosomal subunit

9 of 33

2.39

7.93

2.67e-18

GO:0005761

Mitochondrial ribosome

10 of 60

2.17

7.15

1.45e-18

GO:0044391

Ribosomal subunit

10 of 138

1.81

4.78

7.41e-16

GO:0098798

Mitochondrial protein-containing complex

10 of 163

1.74

4.35

2.63e-15

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4539

Organellar ribosome

10 of 48

2.27

7.86

1.85e-19

CL:4524

Organellar ribosome, and Circadian rhythm - plant

11 of 78

2.1

7.24

2.65e-20

CL:4544

Organellar large ribosomal subunit, and Ribosomal protein L6

7 of 19

2.52

6.7

2.31e-14

CL:4541

Organellar ribosome

8 of 34

2.32

6.68

1.92e-15

CL:4565

Organellar large ribosomal subunit

4 of 7

2.71

3.91

4.67e-08

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 172

1.72

4.18

5.87e-15

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

9 of 264

1.48

2.6

4.22e-10

MAP-392499

Metabolism of proteins

9 of 874

0.96

1.01

7.97e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005762

Mitochondrial large ribosomal subunit

9 of 32

2.4

7.99

2.56e-18

GOCC:0005761

Mitochondrial ribosome

10 of 60

2.17

7.12

1.77e-18

GOCC:0044391

Ribosomal subunit

10 of 145

1.79

4.63

1.36e-15

GOCC:0098798

Mitochondrial protein complex

10 of 159

1.75

4.42

1.96e-15

GOCC:0043229

Intracellular organelle

11 of 3467

0.45

0.38

0.00056

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 113

1.6

1.87

2.31e-05

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