STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bkdCDihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex. (435 aa)    
Predicted Functional Partners:
bkdB_2
3-methyl-2-oxobutanoate dehydrogenase subunit beta.
 
 0.999
bkdB_1
3-methyl-2-oxobutanoate dehydrogenase subunit beta.
 
 0.998
bkdA_2
3-methyl-2-oxobutanoate dehydrogenase subunit alpha.
 
 0.998
bkdA_1
3-methyl-2-oxobutanoate dehydrogenase subunit alpha.
 
 0.996
lpd_2
Dihydrolipoyl dehydrogenase.
 0.996
lpdC
Dihydrolipoyl dehydrogenase.
 0.992
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.986
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
 
0.978
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.967
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.963
Your Current Organism:
Microbacterium ginsengisoli
NCBI taxonomy Id: 400772
Other names: DSM 18659, JCM 15304, KCTC 19189, M. ginsengisoli, Microbacterium ginsengisoli Park et al. 2008, strain Gsoil 259
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.