node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KJL36536.1 | KJL36538.1 | RR49_01546 | RR49_01548 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative heme peroxidase. | 0.837 |
KJL36536.1 | KJL36540.1 | RR49_01546 | RR49_01550 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hypothetical protein. | 0.679 |
KJL36536.1 | cofD | RR49_01546 | RR49_01543 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 2-phospho-L-lactate transferase. | 0.744 |
KJL36536.1 | hemB | RR49_01546 | RR49_01545 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.990 |
KJL36536.1 | hemC | RR49_01546 | RR49_01547 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
KJL36536.1 | hemE | RR49_01546 | RR49_01553 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.957 |
KJL36536.1 | hemH | RR49_01546 | RR49_02480 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.530 |
KJL36536.1 | hemL | RR49_01546 | RR49_01544 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.947 |
KJL36536.1 | hemY | RR49_01546 | RR49_01552 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.730 |
KJL36538.1 | KJL36536.1 | RR49_01548 | RR49_01546 | Putative heme peroxidase. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.837 |
KJL36538.1 | KJL36540.1 | RR49_01548 | RR49_01550 | Putative heme peroxidase. | Hypothetical protein. | 0.659 |
KJL36538.1 | cofD | RR49_01548 | RR49_01543 | Putative heme peroxidase. | 2-phospho-L-lactate transferase. | 0.710 |
KJL36538.1 | ctaB | RR49_01548 | RR49_00210 | Putative heme peroxidase. | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.731 |
KJL36538.1 | hemB | RR49_01548 | RR49_01545 | Putative heme peroxidase. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.831 |
KJL36538.1 | hemC | RR49_01548 | RR49_01547 | Putative heme peroxidase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.838 |
KJL36538.1 | hemE | RR49_01548 | RR49_01553 | Putative heme peroxidase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.689 |
KJL36538.1 | hemH | RR49_01548 | RR49_02480 | Putative heme peroxidase. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.993 |
KJL36538.1 | hemL | RR49_01548 | RR49_01544 | Putative heme peroxidase. | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.801 |
KJL36538.1 | hemY | RR49_01548 | RR49_01552 | Putative heme peroxidase. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.803 |
KJL36540.1 | KJL36536.1 | RR49_01550 | RR49_01546 | Hypothetical protein. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.679 |