| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | gpt | RR49_02080 | RR49_02422 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Xanthine phosphoribosyltransferase. | 0.573 |
| apt | guaA | RR49_02080 | RR49_00645 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.989 |
| apt | guaB_1 | RR49_02080 | RR49_00637 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.898 |
| apt | punA | RR49_02080 | RR49_02335 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.963 |
| apt | purA | RR49_02080 | RR49_02043 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.813 |
| apt | yhcR_1 | RR49_02080 | RR49_01385 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Endonuclease YhcR precursor. | 0.900 |
| apt | yhcR_2 | RR49_02080 | RR49_01388 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Endonuclease YhcR precursor. | 0.797 |
| gpt | apt | RR49_02422 | RR49_02080 | Xanthine phosphoribosyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.573 |
| gpt | guaA | RR49_02422 | RR49_00645 | Xanthine phosphoribosyltransferase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.818 |
| gpt | guaB_1 | RR49_02422 | RR49_00637 | Xanthine phosphoribosyltransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.832 |
| gpt | pat_2 | RR49_02422 | RR49_02424 | Xanthine phosphoribosyltransferase. | Phosphinothricin N-acetyltransferase. | 0.646 |
| gpt | punA | RR49_02422 | RR49_02335 | Xanthine phosphoribosyltransferase. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.744 |
| gpt | purA | RR49_02422 | RR49_02043 | Xanthine phosphoribosyltransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.543 |
| gpt | sdh | RR49_02422 | RR49_02421 | Xanthine phosphoribosyltransferase. | Serine 3-dehydrogenase. | 0.633 |
| gpt | ung | RR49_02422 | RR49_02423 | Xanthine phosphoribosyltransferase. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.798 |
| gpt | yhcR_1 | RR49_02422 | RR49_01385 | Xanthine phosphoribosyltransferase. | Endonuclease YhcR precursor. | 0.708 |
| gpt | yhcR_2 | RR49_02422 | RR49_01388 | Xanthine phosphoribosyltransferase. | Endonuclease YhcR precursor. | 0.708 |
| guaA | apt | RR49_00645 | RR49_02080 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.989 |
| guaA | gpt | RR49_00645 | RR49_02422 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Xanthine phosphoribosyltransferase. | 0.818 |
| guaA | guaB_1 | RR49_00645 | RR49_00637 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |