| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KJL36267.1 | gcvP_1 | RR49_01947 | RR49_02850 | FAD dependent oxidoreductase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.822 |
| KJL36267.1 | gcvP_2 | RR49_01947 | RR49_02851 | FAD dependent oxidoreductase. | Glycine dehydrogenase (decarboxylating). | 0.822 |
| KJL36267.1 | gcvT_3 | RR49_01947 | RR49_02853 | FAD dependent oxidoreductase. | Aminomethyltransferase. | 0.915 |
| KJL36267.1 | gltB_1 | RR49_01947 | RR49_02208 | FAD dependent oxidoreductase. | Glutamate synthase [NADPH] large chain. | 0.947 |
| KJL36267.1 | glyA1 | RR49_01947 | RR49_00159 | FAD dependent oxidoreductase. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.547 |
| KJL36267.1 | rocA | RR49_01947 | RR49_00255 | FAD dependent oxidoreductase. | 1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.675 |
| gcvH_1 | gcvP_1 | RR49_02849 | RR49_02850 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.998 |
| gcvH_1 | gcvP_2 | RR49_02849 | RR49_02851 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating). | 0.993 |
| gcvH_1 | gcvT_3 | RR49_02849 | RR49_02853 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase. | 0.994 |
| gcvH_1 | gltB_1 | RR49_02849 | RR49_02208 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutamate synthase [NADPH] large chain. | 0.909 |
| gcvH_1 | glyA1 | RR49_02849 | RR49_00159 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.901 |
| gcvH_1 | lpd_2 | RR49_02849 | RR49_02109 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase. | 0.890 |
| gcvH_1 | rocA | RR49_02849 | RR49_00255 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.824 |
| gcvH_2 | gcvP_1 | RR49_02852 | RR49_02850 | Glycine cleavage system H protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.993 |
| gcvH_2 | gcvP_2 | RR49_02852 | RR49_02851 | Glycine cleavage system H protein. | Glycine dehydrogenase (decarboxylating). | 0.998 |
| gcvH_2 | gcvT_3 | RR49_02852 | RR49_02853 | Glycine cleavage system H protein. | Aminomethyltransferase. | 0.998 |
| gcvH_2 | gltB_1 | RR49_02852 | RR49_02208 | Glycine cleavage system H protein. | Glutamate synthase [NADPH] large chain. | 0.909 |
| gcvH_2 | glyA1 | RR49_02852 | RR49_00159 | Glycine cleavage system H protein. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.901 |
| gcvH_2 | lpd_2 | RR49_02852 | RR49_02109 | Glycine cleavage system H protein. | Dihydrolipoyl dehydrogenase. | 0.890 |
| gcvH_2 | rocA | RR49_02852 | RR49_00255 | Glycine cleavage system H protein. | 1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.824 |