STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)    
Predicted Functional Partners:
BMY_1179
Thiamine biosynthesis protein ThiS.
  
 0.999
BMY_1177
Sulfur carrier protein ThiS adenylyltransferase.
 
 0.985
thiC
Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 0.979
BMY_1180
Thiamine phosphate synthase.
 
 
 0.970
BMY_0505
Molybdopterin-synthase adenylyltransferase.
 
 0.938
BMY_1392
Molybdopterin synthase sulfur carrier subunit.
   
 
 0.925
thiE
Thiamine phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.871
BMY_1296
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
  
 0.789
BMY_0632
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
  
 0.733
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.705
Your Current Organism:
Wohlfahrtiimonas chitiniclastica
NCBI taxonomy Id: 400946
Other names: CCM 7401, DSM 18708, Ignatzschineria sp. 5401129, W. chitiniclastica, Wohlfahrtiimonas chitiniclastica Toth et al. 2008, strain S5
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