node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BMY_1038 | BMY_1714 | BMY_1038 | BMY_1714 | GMP synthase. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.405 |
BMY_1038 | glmS | BMY_1038 | BMY_1800 | GMP synthase. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.465 |
BMY_1038 | guaA | BMY_1038 | BMY_1969 | GMP synthase. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.808 |
BMY_1038 | purF | BMY_1038 | BMY_0371 | GMP synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.641 |
BMY_1038 | queE | BMY_1038 | BMY_1715 | GMP synthase. | 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.437 |
BMY_1038 | queF | BMY_1038 | BMY_0813 | GMP synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.438 |
BMY_1273 | folE | BMY_1273 | BMY_0324 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | GTP cyclohydrolase I. | 0.983 |
BMY_1273 | queE | BMY_1273 | BMY_1715 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.417 |
BMY_1714 | BMY_1038 | BMY_1714 | BMY_1038 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | GMP synthase. | 0.405 |
BMY_1714 | folE | BMY_1714 | BMY_0324 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | GTP cyclohydrolase I. | 0.957 |
BMY_1714 | gltS-2 | BMY_1714 | BMY_1712 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Sodium:glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. | 0.489 |
BMY_1714 | guaA | BMY_1714 | BMY_1969 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.405 |
BMY_1714 | queC | BMY_1714 | BMY_1713 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.994 |
BMY_1714 | queE | BMY_1714 | BMY_1715 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
BMY_1714 | queF | BMY_1714 | BMY_0813 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.799 |
folE | BMY_1273 | BMY_0324 | BMY_1273 | GTP cyclohydrolase I. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.983 |
folE | BMY_1714 | BMY_0324 | BMY_1714 | GTP cyclohydrolase I. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.957 |
folE | queE | BMY_0324 | BMY_1715 | GTP cyclohydrolase I. | 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.486 |
glmS | BMY_1038 | BMY_1800 | BMY_1038 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthase. | 0.465 |
glmS | guaA | BMY_1800 | BMY_1969 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.465 |