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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV82470.1TIGRFAM: malate synthase A; KEGG: rce:RC1_2688 malate synthase A; PFAM: Malate synthase family protein; Belongs to the malate synthase family. (536 aa)    
Predicted Functional Partners:
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.975
ADV83753.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: aca:ACP_1789 citrate synthase 2; PFAM: Citrate synthase; Belongs to the citrate synthase family.
   
 0.971
ADV82110.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.933
mqo
TIGRFAM: malate/quinone oxidoreductase; KEGG: cpi:Cpin_2378 malate:quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase.
     
 0.922
ADV82847.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 0.920
ADV81965.1
PFAM: pyruvate carboxyltransferase; KEGG: aca:ACP_3471 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.913
ADV82503.1
KEGG: sus:Acid_5289 2-keto-3-deoxy-phosphogluconate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
     
 0.909
ADV82848.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.906
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
     
  0.900
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
     
  0.900
Your Current Organism:
Terriglobus saanensis
NCBI taxonomy Id: 401053
Other names: Acidobacterium sp. SP1PR4, T. saanensis SP1PR4, Terriglobus saanensis SP1PR4, Terriglobus saanensis str. SP1PR4, Terriglobus saanensis strain SP1PR4, Terriglobus sp. SP1PR4
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