| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argG | purA | BDP_1290 | BDP_0089 | argG Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.924 |
| argG | purF-2 | BDP_1290 | BDP_1512 | argG Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | purF Amidophosphoribosyltransferase. | 0.918 |
| argG | purL | BDP_1290 | BDP_0725 | argG Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | purL Phosphoribosylformylglycinamidine synthase. | 0.459 |
| argG | pyrB | BDP_1290 | BDP_1090 | argG Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.909 |
| guaA | guaB | BDP_1005 | BDP_0621 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | guaC | BDP_1005 | BDP_1206 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | guaC GMP reductase,fadD1 Long-chain-fatty-acid--CoA ligase. | 0.999 |
| guaA | hprT | BDP_1005 | BDP_0548 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | hprT Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.970 |
| guaA | purA | BDP_1005 | BDP_0089 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.923 |
| guaA | purB | BDP_1005 | BDP_0760 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | purB Adenylosuccinate lyase. | 0.869 |
| guaA | purF-2 | BDP_1005 | BDP_1512 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | purF Amidophosphoribosyltransferase. | 0.458 |
| guaA | purH | BDP_1005 | BDP_1169 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.789 |
| guaA | purL | BDP_1005 | BDP_0725 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | purL Phosphoribosylformylglycinamidine synthase. | 0.998 |
| guaA | pyrB | BDP_1005 | BDP_1090 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.657 |
| guaB | guaA | BDP_0621 | BDP_1005 | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | guaC | BDP_0621 | BDP_1206 | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | guaC GMP reductase,fadD1 Long-chain-fatty-acid--CoA ligase. | 0.960 |
| guaB | hprT | BDP_0621 | BDP_0548 | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | hprT Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.966 |
| guaB | purA | BDP_0621 | BDP_0089 | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.989 |
| guaB | purB | BDP_0621 | BDP_0760 | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | purB Adenylosuccinate lyase. | 0.878 |
| guaB | purH | BDP_0621 | BDP_1169 | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.975 |
| guaB | purL | BDP_0621 | BDP_0725 | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | purL Phosphoribosylformylglycinamidine synthase. | 0.935 |