STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phophoribosyl transferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (213 aa)    
Predicted Functional Partners:
pyrH
PyrH Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.951
pyrF2
pyrF2 Orotidine 5'-phosphate decarboxylase.
  
 
 0.942
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.942
BDP_1244
Conserved hypothetical protein.
     
  0.900
BDP_1739
5 nucleotidase deoxy cytosolic type C.
     
  0.900
guaA
GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.820
pyrB
Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
  
 0.791
BDP_0831
Phosphoribulokinase (uridine kinase family protein).
  
 
 0.755
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.736
BDP_0204
Phosphohydrolase (MutT/NUDIX family protein); Belongs to the Nudix hydrolase family.
  
    0.643
Your Current Organism:
Bifidobacterium dentium
NCBI taxonomy Id: 401473
Other names: B. dentium Bd1, Bifidobacterium dentium Bd1, Bifidobacterium dentium str. Bd1, Bifidobacterium dentium strain Bd1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.