BDP_0338 protein (Bifidobacterium dentium) - STRING interaction network

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Score

BDP_0338

Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (234 aa)

Predicted Functional Partners:

rplS

0.887

BDP_0337

0.870

BDP_0002

0.858

rnh

0.702

thyA

0.671

recQ

0.637

BDP_0339

0.583

truB

0.569

recA

0.561

BDP_0340

0.560

Your Current Organism:

Bifidobacterium dentium

NCBI taxonomy Id: 401473
Other names: B. dentium Bd1, Bifidobacterium dentium Bd1, Bifidobacterium dentium str. Bd1, Bifidobacterium dentium strain Bd1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDP_0002	BDP_0338	BDP_0002	BDP_0338	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.858
BDP_0002	recA	BDP_0002	BDP_1421	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.834
BDP_0002	recQ	BDP_0002	BDP_0673	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	recQ ATP-dependent DNA helicase recQ.	0.625
BDP_0002	thyA	BDP_0002	BDP_0527	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	thyA Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.725
BDP_0337	BDP_0338	BDP_0337	BDP_0338	lepB Signal peptidase I; Belongs to the peptidase S26 family.	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.870
BDP_0337	BDP_0339	BDP_0337	BDP_0339	lepB Signal peptidase I; Belongs to the peptidase S26 family.	ATP-binding protein of ABC transporter system.	0.465
BDP_0337	BDP_0340	BDP_0337	BDP_0340	lepB Signal peptidase I; Belongs to the peptidase S26 family.	ATP-binding protein of ABC transporter system.	0.465
BDP_0337	rplS	BDP_0337	BDP_0336	lepB Signal peptidase I; Belongs to the peptidase S26 family.	rplS LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.823
BDP_0338	BDP_0002	BDP_0338	BDP_0002	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.858
BDP_0338	BDP_0337	BDP_0338	BDP_0337	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	lepB Signal peptidase I; Belongs to the peptidase S26 family.	0.870
BDP_0338	BDP_0339	BDP_0338	BDP_0339	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	ATP-binding protein of ABC transporter system.	0.583
BDP_0338	BDP_0340	BDP_0338	BDP_0340	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	ATP-binding protein of ABC transporter system.	0.560
BDP_0338	recA	BDP_0338	BDP_1421	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.561
BDP_0338	recQ	BDP_0338	BDP_0673	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	recQ ATP-dependent DNA helicase recQ.	0.637
BDP_0338	rnh	BDP_0338	BDP_0478	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Rnh Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.702
BDP_0338	rplS	BDP_0338	BDP_0336	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	rplS LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.887
BDP_0338	thyA	BDP_0338	BDP_0527	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	thyA Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.671
BDP_0338	truB	BDP_0338	BDP_0467	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	truB tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.	0.569
BDP_0339	BDP_0337	BDP_0339	BDP_0337	ATP-binding protein of ABC transporter system.	lepB Signal peptidase I; Belongs to the peptidase S26 family.	0.465
BDP_0339	BDP_0338	BDP_0339	BDP_0338	ATP-binding protein of ABC transporter system.	Putative ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.583