Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BDP_0526Conserved hypothetical membrane protein. (137 aa)    
Predicted Functional Partners:
fas
Fatty acid synthase Fas.
 
    0.745
acpS
Putative holo-[acyl-carrier protein] synthase3; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
  
    0.744
BDP_0476
Narrowly conserved hypothetical secreted protein.
  
     0.717
BDP_1580
Conserved hypothetical protein.
  
     0.706
thyA
thyA Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.669
BDP_1283
Conserved hypothetical protein.
  
     0.663
BDP_2261
Protein-disulfide isomerase.
  
    0.648
dfrA
dfrA Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
  
  
 0.617
BDP_0759
Conserved hypothetical protein.
 
     0.617
BDP_1938
Conserved hypothetical protein.
  
     0.615
Your Current Organism:
Bifidobacterium dentium
NCBI taxonomy Id: 401473
Other names: B. dentium Bd1, Bifidobacterium dentium Bd1, Bifidobacterium dentium str. Bd1, Bifidobacterium dentium strain Bd1
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