Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Score
ptpAptpA Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (165 aa)    
Predicted Functional Partners:
BDP_1897
Low molecular weight phosphotyrosine protein phosphatase.
  
  
  0.966
BDP_1148
Fructosamine kinase.
     0.858
dfrA
dfrA Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
       0.819
BDP_1816
Low molecular weight protein-tyrosine-phosphatase.
  
     0.765
thyA
thyA Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.723
BDP_0526
Conserved hypothetical membrane protein.
     
 0.604
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
  0.500
trxA
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.449
BDP_1936
Thioredoxin domain-containing protein.
  
 
 0.449
fosC
FosC Beta-fructofuranosidase; Belongs to the glycosyl hydrolase 32 family.
  
 
 0.433
Your Current Organism:
Bifidobacterium dentium
NCBI taxonomy Id: 401473
Other names: B. dentium Bd1, Bifidobacterium dentium Bd1, Bifidobacterium dentium str. Bd1, Bifidobacterium dentium strain Bd1
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